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(Those are not direct comparisons, as the drug were not evaluated in head-to-head clinical trials.) Nausea, constipation and diarrhea were among the side effects of retatrutide they are often seen with GLP-1 drugs

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A randomized controlled trial was carried out to examine the effectiveness of once-weekly subcutaneous semaglutide 2.4 mg as an addition to intensive behavioral therapy and initial low-calorie diet in individuals with overweight or obesity

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